患儿,7岁。气喘,喉间哮鸣,咳嗽痰壅,痰黏色黄难咯,胸闷,呼吸困难,流涕黄稠,烦躁不宁,大便干,咽红,舌质红,苔黄腻,脉滑数。应首选的方剂是
类风湿关节炎的药物治疗中,抗风湿药物首选( )
患者,女,70岁。阵发性心房颤动病史3年,服用“胺碘酮”,近半年来发作较前频繁,每月均有发作,心悸发作持续3d就诊。胺碘酮可能出现的不良反应不包括( )
女,32岁。5d前受凉后出现咽痛、咳嗽,咳少许白色黏痰,发热,体温最高39.7℃,伴畏寒、乏力及全身酸痛,WBC5.2×10⁹/L,N0.56,L0.35,清除患者被感染细胞的主要免疫细胞是( )。
Th17
Treg
CTL
Th2
Th9
Passage1
Lonely people, it seems, are at greater riskthan the gregarious of developing illnesses associated with chronicinflammation, such as heart disease and certain cancers. A paper published lastyear in the Public Library of Science, Medicine, shows the effect on mortalityof loneliness is comparable with thatof smoking and drinking after examining the results of 148 previous studies andcontrolled for factors such as age and pre-existing illness.
Steven Cole of the University ofCalifornia, Los Angeles, thinks he may know why this is so. He told theAmerican Association for the Advancement of Science meeting in Washington,D.C., about his work studying the expression of genes in lonely people. Dr.Cole harvested samples of white blood cells from both lonely and gregariouspeople. He then analysed the activity of their genes, as measured by theproduction of a substance called messenger RNA. This molecule carries instructions from the genes telling a cellwhich proteins to make. The level of messenger RNA from most genes was the samein both types of people. There were several dozen genes, however, that wereless active m the lonely, and several dozen others that were more active.Moreover, both the less active andthe more active gene types came from a small number of functional groups.
Broadly speaking, the genes less active in thelonely were those involved in staving off viral infections. Those that weremore active were involved in protecting against bacteria. Dr. Cole suspectsthis could help explain not only why the lonely are iller, but how, inevolutionary terms, this odd state of affairs has come about.
The crucial bit ofthe puzzle is that viruses have to be caught from another infected individual andthey are usually species-specific. Bacteria, in contrast, often just lurk inthe environment, and may thrive on manyhosts. The gregarious are therefore at greater risk than the lonely ofcatching viruses, and Dr. Cole thussuggests that past evolution has created a mechanism which causes white cellsto respond appropriately. Conversely, the lonely are better off ramping uptheir protection against bacterialinfection, which is a bigger relative risk to them.
What Dr. Cole seemsto have revealed, then, is a mechanism by which social environment reachesinside a person's body and tweaks its genome so that it responds appropriately.It is not that the lonely and the gregarious are genetically different fromeach other. Rather, their genes are regulated differently, according to howsociable an individual is. Dr. Cole thinks this regulation is part of a widermechanism that tunes individuals to the circumstances they find themselves in.
What can we know about viruses and bacteria from the fourth paragraph?
某酒店在装修时发生坍塌事故。经调查,酒店存在违法发包,施工单位未经许可擅自施工并改动建筑主体和承重结构等行为。根据《建筑法》,关于建设、施工单位安全管理及法律责任的说法,正确的是( )。
如果被审计单位以养殖牲畜为主要业务,那么注册会计师针对该类存货可以实施的监盘程序中效果最好的是( )。